If long-term, single, and repeated use of the same agent to prevent and control the same pests and diseases, there will be a phenomenon in which the efficacy of the drug is significantly reduced or even ineffective. This phenomenon is called resistance to insects and diseases. The emergence of resistance to pests and diseases not only has a serious negative impact on the efficacy of the pesticide factory, but also causes an increase in production costs and a decline in the control effect. At the same time, blind drug use can also cause soil environmental pollution and damage the ecological balance. In order to reduce and prevent the occurrence of drug resistance, the following points must be noted when using pesticides:
[Rotate (alternate) medication] Single-species pesticides can induce drug resistance, and biological pesticides and antibiotics and pesticides can be used in rotation to prevent the formation of drug-resistant populations in biological populations. Alternate medication is the use of pesticides with completely different mechanisms of action during a certain growth period of the plant. This will increase the effectiveness of the control and extend the useful life of certain excellent pesticides. For example, pesticides such as organophosphorus preparations, pyrethroids, carbamate preparations, organic nitrogen preparations, and biological preparations have different mechanisms of action. Pesticide varieties in the same type of preparation can also be used interchangeably, but it is necessary to know whether there is cross-resistance between them.
[reasonable mixing] Mixing agents with different modes of action and mechanisms can also slow down the rate of drug resistance. For example, when crops are resistant to pyrethroid pesticides, organic phosphorus and pyrethroid pesticides are used in combination to suppress the resistance of pests. Single point pesticides are mixed with traditional pesticides with multiple points, and the effect is better. It should be noted that the mixed pesticides can not be used for a long time, and it is necessary to rotate the drugs, otherwise it will also cause drug resistance.
[Intermittent medication] If a pesticide has been found to have great resistance, it should be discontinued or discontinued. When a drug has already caused drug resistance, if it is stopped for a period of time, the drug resistance phenomenon may gradually decrease or even disappear, such as the resistance caused by monocrotophos. After several years of inactivity, the drug resistance basically disappears.
[Scientific Application] The effective dosage and uniform distribution of the drug in the field are essential. For different plants and different pests, appropriate application techniques should be used. Do not increase the dosage and increase the number of medications. Therefore, a better control effect can be obtained with a smaller amount.
[Application of synergists] Synergists can increase the biological activity of pesticides and improve drug efficacy. Adding a certain amount of synergist to some pesticides is a very effective way to delay or overcome the resistance of pests and diseases. Note that the synergist used must be an authentic and pure synergist, not a pesticide-added formulation. For example, the high-profile well-known pesticide synergist in the market.
[Adhere to comprehensive prevention and control methods] Diseases and insect pests occur in various factors such as soil, climate, cultivation management, etc., and adopt a single control measures, especially chemical control, which is easy to produce drug resistance. The combination of chemical control, biological control, and force control can be combined and integrated to prevent and prevent drug resistance.
Chemical intermediate, any chemical substance produced during the conversion of some reactant to a product. Most synthetic processes involve transformation of some readily available and often inexpensive substance to some desired product through a succession of steps. All the substances generated by one step and used for the succeeding step are considered Intermediates.
Intermediates
Medical Intermediate,Pharmceutical Intermediates,Agrochemical Intermediates,Dye Intermediate
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