Analysis of Tea Polyphenols Antitumor and Regulation of Immunity

Business News Agency June 27th National Natural Science of China ** In 1995, the “Anticancer Mechanism of Effective Components of Tea” was used as a key subject for tender research, and clinical observations have also achieved good results. The results showed that the main anti-cancer components of tea are the tea catechin monomers and the various catechin monomers and tea polyphenols oxidation products tea pigment.

See the scientist's experiment:

1. Epidemiological studies Animal experiments over the years have repeatedly demonstrated that tea preparations and tea polyphenols can inhibit the formation and growth of malignant tumors induced by some physical factors or chemical carcinogens.

2. Intervention trials Intervention trials on high-risk cancer patients showed that drinking mixed tea (green tea lyophilisate, tea polyphenols, and tea pigment mixture) had protective effects on DNA damage of human oral mucosal epithelial cells and had a preventive effect on oral cancer. Tea polyphenols have a protective effect on human DNA damage caused by smoking and reduce the incidence of tumors caused by smoking. Tea polyphenols have a preventive effect on the occurrence of gastrointestinal cancer.

3. Clinical observation Myelosuppression is a common toxic reaction during chemotherapy and radiotherapy. Tea polyphenols have a significant protective effect on cisplatin-treated patients' hemograms, and in particular have a significant effect on stabilizing the white blood cell count of cisplatin-treated patients.

4. Animal experiments A variety of animal experiments have shown that tea polyphenols can significantly inhibit the formation, growth and malignant metastasis of experimental mouse skin tumors and lung tumors; green tea extracts can significantly inhibit the growth of rat gastrointestinal tumors; tea polyphenols It can significantly reduce the incidence of colon cancer in mice and reduce colonic follicle formation in rats. Green tea extract and EGCG (tea polyphenols) also have significant inhibitory effects on gastric cancer and colon cancer.

Tea polyphenols also have the effect of modulating immunity. Animal experiments show that tea polyphenols can increase the relative weight and cell number of the spleen to adjust the immune function of tumor-bearing mice; and promote the proliferation of immune cells by significantly increasing the number of thymus or spleen cells per gram of ascites tumors and sarcoma mice.

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